BRUSSELS—Austria went into a major lockdown on Monday to try to break the strong fourth wave of Covid spreading across Europe, while the German health minister, Jens Spahn, warned that by the end of this winter“just about everyone in Germany will probably be either vaccinated, recovered or dead.”

While countries with high vaccination rates—including Portugal, Italy, and Spain—have experienced an uptick in cases, the outbreak has hit hardest in countries with large pockets of unvaccinated people, especially in Central and Eastern Europe.

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